Sherrock who made history at the 2020 PDC World Championship in becoming the first woman to claim a win in the tournament, has not played in competitive action since Q-School due to exhibitions and not playing on the Challenge Tour or WDF circuit.
The Milton Keynes ace will line-up alongside Beau Greaves, with the 16-year old set to receive her first call-up.
Also in the side includes the likes of former World Master Lorraine Winstanley, Maria O'Brien and captain Deta Hedman who all retain their places. Sue Gulliver also receives her first call-up in some time.
Martin Adams will lead the men's side as captain after Scott Mitchell decided to sit out the British Internationals.
Paul Hogan retains his place alongside Daniel Day, Kevin Dowling, Nigel Heydon and Paul Milford. There are debuts for John Mann alongside Allan Edwards, David Evans, Nick Fullwell and Justin Hood.
Dave Parletti also returns to the line-up having been absent 12 months ago. Brad Phillips retains his place in the Boys squad with some of the JDC's best in Tavis Dudeney, Nathan Potter and Luke Littler making their debuts.
Shannon Reeves and Holly Meadwell will form part of the Girls' Squad with Greaves making the step up to senior level so there is only two involved in the event which takes place from April 3-5 from Lincolnshire.
British Internationals
Men's Squad
Martin Adams (C)
Daniel Day
Kevin Dowling
Allan Edwards
David Evans
Nick Fullwell
Nigel Heydon
Paul Hogan
Justin Hood
John Mann
Paul Milford
Dave Parletti
Ladies' Squad
Deta Hedman (C)
Maria O’Brien
Beau Greaves
Lorraine Winstanley
Sue Gulliver
Boys Squad
Brad Phillips
Tavis Dudeney
Luke Littler
Nathan Potter
Girls' Squad
Shannon Reeves
Holly Meadwell