Rob Cross and Gerwyn Price will face Cristo Reyes and Krzysztof Ratajski and will look to avenge defeats they suffered to the latter.
Of the other games, there will be a quick fire contest between Michael Smith who has been playing injured; but still producing the goods against the in-form Jermaine Wattimena.
James Wade will face a tricky test in Ross Smith who has been going under the radar in this tournament so far and Nathan Aspinall will take on Steve Lennon in a battle of the Premier League contenders.
Board allocations will be revealed shortly before the matches later this evening with only the main stage and board two still in action at this late stage.
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UK Open including the schedule, prize fund breakdown, TV coverage and format.
Draw - Sixth Round UK Open Rob Cross v Cristo Reyes
Krzysztof Ratajski v Gerwyn Price
Steve Beaton v Dimitri Van den Bergh
Michael Smith v Jermaine Wattimena
Dave Chisnall v Simon Stevenson
James Wade v Ross Smith
Simon Whitlock v Josh Payne
Nathan Aspinall v Steve Lennon