Van Barneveld was unable to challenge Dave Chisnall (1-6), while Lewis came up short against Keegan Brown: 3-6. Gary Anderson lost out in a deciding leg against a resurgent Benito van de Pas. Kim Huybrechts, Stephen Bunting and Kyle Anderson were among the other players eliminated.
Terry Jenkins reached the last 16 of a PDC-event for the first time since 2016 with a 6-3 win over Cristo Reyes. The Raging Bull had already knocked out Maik Langendorf and Mervyn King in his first two matches.
World-number-one Michael van Gerwen comfortably held off Josh Payne, with fellow Premier League stars Michael Smith and Rob Cross getting the better of Stephen Burton and Arron Monk respectively.
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Last 32
Michael van Gerwen 6|1 Josh Payne
Danny Noppert 6|5 William O'Connor
Dave Chisnall 6|1 Raymond van Barneveld
Keegan Brown 6|3 Adrian Lewis
James Wilson 6|2 Jamie Bain
Ian White 6|2 Jonny Clayton
Michael Smith 6|1 Stephen Burton
Gerwyn Price 6|3 Stephen Bunting
Ryan Joyce 6|1 Wayne Jones
Michael Barnard 6|0 Kyle Anderson
Ron Meulenkamp 6|1 Kim Huybrechts
Terry Jenkins 6|3 Cristo Reyes
James Wade 6|1 Chris Dobey
John Henderson 6|2 Peter Hudson
Rob Cross 6|2 Arron Monk
Benito van de Pas 6|5 Gary Anderson