A new home of the Morningside Arena, home of British Basketball side Leicester Riders will host the event for the first time.
Two matches from both Groups will take place in each session with Michael Smith against Gary Anderson and Michael Van Gerwen versus James Wade the standouts.
As well in Group B, Daryl Gurney against Peter Wright and Rob Cross against Gerwyn Price will headline a stacked afternoon session on opening day.
Afternoon session's winning players face each other, and losing players face each other after that in the evening session allowing the groups to be almost finalised.
Remaining group games take place on Sunday afternoon; with a champion then crowned in the evening.
Click here to view the lineup in full for the event.
2019 Paddy Power Champions League of Darts Schedule of Play Saturday October 19 Afternoon Session (1230 BST Start)
4x Group Matches
Daryl Gurney v Peter Wright (Group B)
Rob Cross v Gerwyn Price (Group B)
Michael Smith v Gary Anderson (Group A)
Michael van Gerwen v James Wade (Group A)
Evening Session (1830 BST Start)
4x Group Matches
Afternoon session's winning players face each other, and losing players face each other.
Sunday October 20
Afternoon Session (1230 BST Start)
4x Group Matches
Remaining group matches.
Evening Session (1830 BST Start)
Semi-Finals
Final