Burton won two of the first four legs against Van Gerwen, but was not able to keep pace with the two-time world champion. The world number one rushed into a 6-2 lead, before the Ipswich ace won another two legs and reduced the deficit to 7-4.
However, Van Gerwen found the accelerator again and came with 11- and 12-dart legs to move one leg away from victory. 'Mighty Mike' then secured the victory with an 83 checkout.
Clayton also booked a convincing victory as he defeated Ricky Evans 10-5. The Welshman averaged 90 with only 24 percent on the doubles.
Click here for more information about the Players Championship Finals.
James Wade (89.00) 9-10 (87.34) Chris Dobey Gary Anderson (100.58) 10-2 (91.78) Joe Cullen
Michael van Gerwen (104.06) 10-4 (93.65) Stephen Burton 22:10 Peter Wright v Stephen Bunting Steve Lennon (92.35) 10-7 (90.44) Gabriel Clemens Brendan Dolan (94.39) 6-10 (101.79) Daryl Gurney
Jonny Clayton (89.62) 10-5 (90.08) Ricky Evans 22:00 Krzysztof Ratajski v Danny Noppert